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br Vector construction Total RNA at a concentration
2018-11-03
Vector construction Total RNA at a concentration of 0.05µg/µL was reverse transcribed with a cDNA cycle kit (Invitrogen, Karlsruhe, Germany) using oligo dT primers and AMV reverse transcriptase. Amplification of the complete cathepsin L coding sequence was by PCR with 500ng cDNA using 0.5µM each
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br Acknowledgments The CSGID project has been funded in whol
2018-11-03
Acknowledgments The CSGID project has been funded in whole or in part with Federal funds from the National Institute of Allergy and Infectious Diseases, National Institutes of Health, Department of Health and Human Services, under Contracts nos. HHSN272200700058C and HHSN272201200026C. We thank S
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A neuroinflammatory response typically occurs when signals i
2018-11-03
A neuroinflammatory response typically occurs when signals involving infection or irritation are evoked in the brain, or through vagal afferents, transport of cytokines into the tamoxifen citrate through the blood–brain-barrier (BBB), or infiltration of cytokines where the BBB is absent (Schoderboe
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Finally we expected that the cannabis only
2018-11-03
Finally, we expected that the cannabis-only group would show increased reward responding in the NAcc compared to the tobacco-only and control groups. However, no differences emerged between the cannabis-only group and any of the other groups. Importantly, cannabis use is becoming increasingly normat
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A growing body of literature
2018-11-03
A growing body of literature suggests that Major Depressive Disorder (MDD) is associated with impaired cognitive control processes necessary for effective emotion regulation (Diener et al., 2012). These impairments are often coupled with ineffective or maladaptive regulation strategies that may exac
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Many risk factors may lead to disrupted language
2018-11-03
Many risk factors may lead to disrupted language development (Bishop et al., 2003; Rice, 2012; Zubrick et al., 2007). One predictor drawing attention is early receptive language skill. Evidence suggests that propyl the receptive language status of a late-talking child is predictive of expressive la
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Although not surviving correction for multiple comparisons h
2018-11-03
Although not surviving correction for multiple comparisons, high levels of both guilt and shame-proneness were associated with attenuated dmPFC cortical thinning with age. The involvement of the dmPFC in shame is consistent with hypotheses and with previous fMRI study findings (Roth et al., 2014). T
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br Amygdala striatal interactions in maturity The
2018-11-03
Amygdala-striatal interactions in maturity The unidirectional glutamatergic projections from the BLA to the ventral striatum (Everitt et al., 1991; Groenewegen et al., 1999; Robbins et al., 1989) facilitate the ventral striatum’s role as an interfacing region able to translate evaluative signals
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The Social Re Orientation framework Nelson et al
2018-11-03
The Social Re-Orientation framework (Nelson et al., 2005) focuses on how adolescent social behavior is rooted in the development of androgen receptor inhibitor regions nested across a social information processing network (SIPN) of nodes. The detection node, which is already well-developed in early
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Similarly in human participants there is evidence of
2018-11-03
Similarly, in human participants, there is evidence of hippocampal activation as measured by magnetoencephalography (MEG) during performance of transverse patterning (Hanlon et al., 2003; Moses et al., 2009). Interestingly, hippocampal activity decreased and MTL cortical activity increased when sema
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Such discrepancies highlight several critical limitations
2018-11-03
Such discrepancies highlight several critical limitations of the present study. One limitation concerns the fact that we used the ELEQ to measure children’s exposure to adversity. The use of the ELEQ reflects our interest in normative variation in adversity; however, this measure has not been widely
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br Data br Experimental design material and methods br Data
2018-11-03
Data Experimental design, material and methods Data The dataset contains 15 files of temporal series that represent 15 different situations related to 5 operational scenarios. Files’ duration varies depending on the situation and dysfunctional component. Accordingly, affected components are
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Introduction Psoriasis is a chronic inflammatory
2018-11-03
Introduction Psoriasis is a chronic inflammatory dermatological disorder that impairs the quality of life of patients both physically and psychologically. Its prevalence is estimated to be 2%, and the total rate of psoriasis in children younger than 18 years old, including about 3.5–16% infantile p
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br Introduction The epidermal permeability barrier is one of
2018-11-03
Introduction The epidermal permeability barrier is one of the most crucial protective functions of the skin and is primarily mediated by stratum corneum lipids and differentiation-related proteins. Stratum corneum lipids consist mainly of an equal molar ratio of cholesterol, fatty acids, and cera
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br Case Report A year old
2018-11-03
Case Report A 40-year-old male patient presented with a complaint of excessive sweating on the right side of the face and the left side of the waist lasting 5 years. He had no prior traumatic event, pyretic disease, or stroke before these symptoms developed. Dermatological examination demonstrate
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