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The FRGN strain developed herein
2018-11-12
The FRGN strain developed herein is suitable for hematopoietic reconstitution and in addition to this has some other advantages over our originally reported FRG KO on the C57BL6 strain (Azuma et al., 2007). While the final percentages of highly reconstituted (>80%) mice did not differ significantly
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PD173074 br Materials and methods br
2018-11-12
Materials and methods Results and discussion By analyzing surface markers of PD173074 isolated from PD effluents, we identified a Lin−/CD34+/CD38−/CD90+ (~0.14±0.03%) subpopulation (Fig. 1A), which are known to enrich for human HSCs. PD cells also contain phenotypic hematopoietic progenitors
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br Materials and methods br
2018-11-12
Materials and methods Results Discussion Murine embryonic stem purchase HBTU have been shown to be responsive to IFN-α and IFN-β (Whyatt et al., 1993). The undifferentiated hESC and iPSC showed an attenuated type I interferon response that correspond to high expression of SOCS1, a suppress
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We became interested in the potential role of ADF genes
2018-11-12
We became interested in the potential role of ADF genes and Cyanine3.5 alkyne dynamics during osteoblast (OB) differentiation of hMSCs for several reasons. First, actin and microtubules are abundant in osteoblasts (Aubin et al., 1983; Arena et al., 1991). During OB differentiation, cell morphology
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Some of the cultured cardiac MSCs also stained positive for
2018-11-09
Some of the cultured cardiac MSCs also stained positive for the mesodermal progenitor marker TBX18 (Mommersteeg et al., 2010; Christoffels et al., 2006); future studies need to be performed in order to address whether some of the PDGFR-α+ and TBX18+ nicotinic receptor agonist potentially share a dev
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br Acknowledgment The study has been
2018-11-09
Acknowledgment The study has been sponsored by a Russian Science Fund grant (project no. 15-19-00091). Introduction The issue of the flow and heat transfer in cross-flowed tube bundles is among the most practically important ‘canonical’ cases [1,2] of the problem on liquid metal coolant therm
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br Conclusion br Introduction Platinum group metals
2018-11-09
Conclusion Introduction Platinum group metals (PGMs) are applied in several different industries, hence the interest in developing methods for their separation (Kolekar and Anuse, 2002). Rhodium, for example, has been in demand in recent years since it is indispensable in automotive catalytic
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Emotion regulation is defined as modulating the valence inte
2018-11-09
Emotion regulation is defined as modulating the valence, intensity, or time-course of an emotional experience (Thompson, 1994). These emotional experiences can range across basic and complex emotions, but, in early childhood, the regulation of anger and frustration is particularly salient as childre
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Enteric bacteria have been implicated in cancer
2018-11-09
Enteric bacteria have been implicated in cancer progression of the gut (Louis et al., 2014; Schwabe and Jobin, 2013). Their increased abundance in bile duct tissues could promote tumorigenesis in a similar manner. Indeed, the data in this study supports an increase in the microbial production of car
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The strong negative association between IgG and
2018-11-09
The strong negative association between IgG and IgM levels and CHD events needs to be considered in the context of other biomarkers that have been evaluated as adjuncts to traditional risk assessments. Although the ASCOT-CRP substudy concluded that measuring CRP had little utility in refining CV ris
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There are additional important noteworthy
2018-11-09
There are additional important noteworthy points. Although both retinal pigment epithelial cyclosporin (RPE) and endothelial cells showed glucose induced reduction of miR15a and associated alteration, overexpression of miR15a in the endothelial cells (as Tie2 is not expressed in the RPE) prevented
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enba br Conclusion br Disclosure The
2018-11-09
Conclusion Disclosure The authors declare no conflicts of interest. I.R. is supported by the Wellcome Trust [103952/Z/14/Z]. Hepatocellular carcinoma (HCC) is a type of liver cancer, causing the highest mortality in the world (). Although surgical operation or other intervention therapies a
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br Methods Estimates of grid coverage and grid connectivity
2018-11-09
Methods Estimates of grid coverage and grid connectivity in developing countries suffer from uncertainty and measurement error. There is a need for better data on the extent to which unelectrified rural households and businesses are truly “off grid,” and the barriers to last-mile electrification
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Apart from the above fat preference
2018-11-09
Apart from the above fat-preference angle, we also found that a genetic variant of the FTO gene, the best known genetic risk factor for obesity, predicts an inverse relationship between total Digoxigenin-11-UTP volume and fat body mass (Melka et al., 2013b). We have suggested that, given the comple
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Here we use T weighted
2018-11-09
Here we use T2*-weighted EPI (T2*) to characterize age-related differences in the neurophysiology of the human adolescent striatum in vivo using a multivariate pattern analysis approach. Specifically we use spatial patterns of striatal T2* to generate highly significant age predictions from both tas
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