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Brugada syndrome BS is a hereditary
2019-05-09

Brugada syndrome (BS) is a hereditary arrhythmogenic disease characterized by a coved- or saddleback-type ST elevation in the right precordial lead on a 12-lead electrocardiogram (ECG) and ventricular fibrillation (VF) occurring mainly at night. During the past 2 decades, since Brugada and Brugada
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The effects of zoledronic acid are
2019-05-09

The effects of zoledronic TH-302 are most likely due to impairment of the tumour-driven alterations to the bone microenvironment. This may render the bone marrow cavity unfavourable for metastatic growth, potentially redirecting tumour cells to other sites, including the periosteal surface. Whereas
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MK-1775 In addition our present findings demonstrated that N
2019-05-09

In addition, our present findings demonstrated that NOACs may offer advantages over warfarin therapy besides efficiency and safety. The time to ECV in the present OAC-naïve patients was significantly shorter in the NOAC group compared to the VKA group. This may be explained by the delayed achievemen
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In contrast to adults PBL
2019-05-08

In LY2606368 to adults, PBL in children is regarded as a clinical entity that is distinct from its adult counterpart. Like many other pediatric malignancies, PBL is considered a systemic disease in children. In small retrospective studies, PBL in children is characterized by rapid progression, a hi
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Changing the pacemaker mode to VDD is a good
2019-05-08

Changing the pacemaker mode to VDD is a good approach in cases of normal sinus node function and loss of atrial lead capture, especially if atrial sensing is stable. In this case, Short AV delay is a good way to reduce the risk of R on T phenomenon which is theoretically possible if a ventricular ec
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Current treatment options for paroxysmal supraventricular ta
2019-05-08

Current treatment options for paroxysmal supraventricular tachycardias include AV Erastin blocking agents (verapamil, diltiazem, propranolol, and metoprolol), class IC anti-arrhythmic agents (propafenone and flecainide), and catheter ablation. The identification of frequent coexistence of clinical,
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Coincidente con esta perspectiva Tadeo
2019-05-08

Coincidente con esta perspectiva, Tadeo es un escritor que busca alejarse del vulgo y considera que la gran literatura no puede ser comprendida por todos. Su ensimismamiento lo conduce al desprecio por los otros y full read un aislamiento extremo, donde al final ni siquiera es capaz de cubrir sus ne
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br Introduction Liver fibrosis cirrhosis
2019-05-08

Introduction Liver fibrosis/cirrhosis is a global health problem that leads to morbidity and mortality. Alcohol abuse is one of the most common causes of liver fibrosis/cirrhosis in western developed countries and accounts for more than 50% of cirrhosis cases. Alcoholic liver fibrosis is characte
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To the best of our knowledge
2019-05-08

To the best of our knowledge, only one other group studied low-dose protracted oral clofarabine in MDS patients who failed hypomethylating agents. They studied 5mg (fixed dose) daily for 10 consecutive days of a 28-day cycle. All patients who were treated for 10 days had a greater than 25% drop in t
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The type of ventricular arrhythmia monomorphic VT or polymor
2019-05-08

The type of ventricular arrhythmia (monomorphic VT or polymorphic VT/VF) responsible for the electrical storm provides an important diagnostic clue to its pathophysiology (Fig. 1). In this review, we address the diagnosis and specific treatments according to the type of ventricular arrhythmia and th
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Involvement of the ventricular myocardium can lead to
2019-05-08

Involvement of the ventricular myocardium can lead to delayed conduction or anatomical obstacles that are labile to ventricular tachyarrhythmia. Arrhythmias are independently predictive of sudden cardiac death (SCD) [9]. SCD is common in patients with cardiac AL amyloidosis, and prophylactic implant
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Because of high suspicion of malignancy we chose
2019-05-08

Because of high suspicion of malignancy, we chose endoscopic ultrasound (EUS) instead of MRI of the pancreas to detect the organic lesion that caused the distal CBD stricture because initial abdominal CT did not show any suspicious lesion in the pancreas. In addition, tissue sample could be obtained
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egfr pathway br Future directions There is increasing eviden
2019-05-08

Future directions There is increasing evidence that osteoblasts are important components of the bone metastatic niche, but their precise contribution in supporting tumour cell engraftment, dormancy and survival remains to be defined. Unlike osteoclasts, the role of osteoblasts in bone metastasis
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The miR signature of exosomes isolated from bulk prostate
2019-05-08

The miR signature of exosomes isolated from bulk prostate cancer AZD 7762 (Fig. 1A, blue cells) and from their cancer stem cell compartment (Fig. 1A, green cells), display high levels of miR-21, miR-30 and miR-218 [23] (Fig. 1A, blue arrow). miR-21 and miR-30 have been identified as key regulators
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Clinical symptoms consist of the pacemaker
2019-05-07

Clinical symptoms consist of the pacemaker syndrome, including palpitations and hemodynamic instability, as in our case. The definitive management of RNRVAS requires sufficient time for the atrial tissue to recover from the refractory period. Barold et al. reviewed several general modes that could p
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