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br Conclusion Accumulating clinical data suggest
2019-04-17
Conclusion Accumulating clinical data suggest the presence of a genetic component in the pathogenesis of AF. In addition to the gene mutations identified in familial AF, the candidate gene approach and GWAS identified genetic risks in the non-familial form of AF. In multiple Western populations,
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The authors would like to thank Ms Fang Ju
2019-04-17
The authors would like to thank Ms. Fang-Ju Sun for her help with statistical analysis. This study was supported by a research grant from Mackay Memorial Hospital (MMH10466). Introduction Cancer of the Silmitasertib (CC) is the second most common cancer affecting women worldwide, and about 86% o
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El trasfondo musical de la obra de sor Juana In
2019-04-17
El trasfondo musical de la obra de sor Juana Inés de la Cruz ha recibido la atención de connotados críticos, tanto del ámbito de la música como del de las letras. Quien parece haber inaugurado en toda forma esta veta crítica es Alfonso Méndez Plancarte en su admirable anotación de la obra de sor Jua
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Stimulated IUI is much more effective than natural cycle or
2019-04-17
Stimulated IUI is much more effective than natural BTL-104 or controlled ovarian hyperstimulation treatment. In four randomized trials of patients with unexplained subfertility, pregnancy rates were higher when IUI was performed in stimulated cycles than in natural cycles [odds ratio (OR): 2.14; 95
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br CaMKII and heart failure progression CaMKII is a
2019-04-17
CaMKII and heart failure progression CaMKII is a multifunctional serine–threonine kinase, phosphorylating target proteins. Under resting conditions, CaMKII is inactive. A rise in intracellular Ca2+ stimulates binding of Ca2+ to calmodulin (CaM), a ubiquitous Ca2+-binding protein. The Ca2+/CaM com
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br Future potential cardiac examinations for long
2019-04-17
Future potential cardiac examinations for long-duration spaceflights Currently available treatments for emergency cases in spaceflight Astronaut Crew Medical Officers (CMO) aboard the ISS receive 40–70h of medical training, including CPR training, within 18 months preceding their mission (Fig.
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Univariate analysis for overall survival revealed that age
2019-04-17
Univariate analysis for overall survival revealed that age (≤, >50 years), menopausal status, T-N stage, and histological tumor size were statistically significant factors for survival. Menopausal status was determined after two years of amenorrhea. In post-menopausal women, the disease-free surviva
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br Results br Discussion The
2019-04-17
Results Discussion The results of this retrospective study demonstrate the feasibility and safety of combined left atrial catheter ablation and Watchman® implant procedures with satisfactory LAA occlusion maintained at follow-up. The rates of successful device implantation and complete LAA occ
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En Sumar restar Carlos Fuentes efectivamente colabora con K
2019-04-17
En Sumar, restar, Carlos Fuentes efectivamente colabora con Kátharsis; elige, con cierta ironía, el diálogo escénico, la forma clásica señalada por Aristóteles para la catarsis; pone en acción aromatase inhibitor tres personajes, un griego (Pitágoras), a una forma pura (el número uno) y a un mexican
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leukotriene receptor antagonist Mechanistic target of rapamy
2019-04-17
Mechanistic target of rapamycin (mTOR), a highly conserved serine-threonine protein kinase, is a key regulator of cell growth and metabolism. As discussed above, mTORC1 is a negative regulator of the preinitiation complex that modulates the initiation of autophagosome biogenesis. Pharmacological and
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Si en La virgen de los sicarios la vida crapulosa
2019-04-17
Si en La virgen de los sicarios “la vida crapulosa está derrotando ap-1 transcription factor la muerte”, y “anda toda ventiada por Medellín día y noche en su afán haciendo lo que puede, compitiendo con semejante paridera, la más atroz [y] este continuo nacer de niños y el suero oral le están sacando
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The risk of breast cancer development in
2019-04-16
The risk of breast cancer development in men with Klinefelter syndrome is 20 times that in men without the syndrome. Gynecomastia occurs after puberty in about 85% of male patients with Klinefelter syndrome. These conditions are related to hormonal imbalance with low plasma testosterone and high est
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Studies and reports of lung metastasis of GCTB are rare
2019-04-16
Studies and reports of lung nimesulide of GCTB are rare because of the low incidence of lung metastasis. The biological behavior and clinical features of GCTB are difficult to predict [6,7]. Some researchers have attempted to analyze related clinical factors of lung metastasis, such as age, sex, pri
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Los principios de Promover intercambio de informaci
2019-04-16
Los principios de Promover intercambio de información junto con el de Mantener acuerdos y arreglos bilaterales y regionales son inseparables del principio de Cooperación y emergen de manera directa del mismo. El accionar de los estados miembros que conforman una organización interregional, consolida
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mek162 HCV does not kill the
2019-04-16
HCV does not kill the mek162 it infects, but triggers an immune-mediated inflammatory response (hepatitis) that either rapidly clears the infection or slowly destroys the liver, causing the development of HCC and cirrhosis. The outcome is largely determined by the efficiency of the antiviral immune
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