• br Since the publication of Stillbirths Series

  2019-05-23

  

  Since the publication of Stillbirths Series in 2011, attention to the more than 2·6 million stillbirths that occur every year has become more visible in global and national maternal and neonatal health strategies. However, we continue to neglect the millions of women who experience not only still

• Randomised controlled trials of educational

  2019-05-22

  

  Randomised controlled trials of educational interventions have also reported evidence to support the view that increased education is likely to be protective against infection. However, most education-focused trials are not designed to detect low-probability events such as HIV or to study the cumula

• In the APHRS survey most respondents answered

  2019-05-22

  

  In the APHRS survey, most respondents (86%) answered that OACs were discontinued before endoscopy or surgery. With novel OACs, physicians will be able to discontinue anticoagulant therapy before the surgical procedure without concern for thrombotic complications. The APHRS survey did not investigate

• Bafetinib Supplier br As the only methods available for dual

  2019-05-22

  

  As the only methods available for dual protection against pregnancy and sexually transmitted infections (STIs), male and female condoms have a vital role in sexual and reproductive health. Mags Beksinska and colleagues therefore are to be commended for their randomised crossover trial in this Bafe

• br Discussion ATRA and arsenic are both

  2019-05-22

  

  Discussion ATRA and arsenic are both known to induce differentiation syndrome but this case was notable for its severity. Previous studies of differentiation syndrome have demonstrated that APL mk-801 treated with ATRA secrete the chemokines CCL2 and IL-8, which in combination with chemokine pro

• br AML therapies with curative intent br

  2019-05-22

  

  AML therapies with curative intent Alternative treatment strategies Targeted therapies: the new kids on the block The recognition of specific mutations as genetic drivers or facilitators of AML has led to the development of new inhibitors and targeted treatment options. New promising drug c

• Interpretation The SMART course can give orthopaedic surgeon

  2019-05-22

  

  Interpretation The SMART course can give orthopaedic surgeons practising in LMICs the skills and knowledge to successfully perform flaps and reduce amputation. While this erk inhibitor course offers a collaborative, sustainable approach to reduce global surgery disparities in amputation, future inv

• Common and rare SCN A variants may contribute

  2019-05-22

  

  Common and rare SCN10A variants may contribute to AF susceptibility [59,60]. SCN10A mutations (R14L and R1268Q) cause a loss of function of Nav1.5 current, which is expected to reduce excitability and lead to the development of the arrhythmogenic substrate responsible for BrS and AF. A common varian

• It is noted that in this study BrS

  2019-05-22

  

  It is noted that in this study BrS patients had an abnormality of plasma K+ concentration which has been suggested to be a potential trigger of Brugada Syndrome episodes [11]. In the absence of renal dysfunction, the hyperkalemia may result from an abnormal phenotype in BrS characterized by mutation

• Nademanee et al reported nine symptomatic

  2019-05-22

  

  Nademanee et al. reported nine symptomatic patients with BrS who experienced VF and underwent electrophysiological study and catheter ablation [8]. The patients exhibited abnormal epicardial electrograms characterized by fragmented electrograms with a relatively low voltage ( Idiopathic ventricular

• br Discussion Pericardial adhesions often develop after open

  2019-05-22

  

  Discussion Pericardial adhesions often develop after open alzheimer\'s association surgery, rendering a percutaneous subxiphoidal pericardial approach challenging [1–5]. Such adhesions are anticipated to be less dense in the inferior wall than in the anterior wall of the LV [1]. Therefore, there

• br La poes a temprana de Carlos

  2019-05-22

  

  La poesía temprana de Carlos Pellicer (1899–1977) ejemplifica un cambio fundamental en la lírica hispanoamericana. Su obra revela la transición entre el cosmopolitismo ahistórico y exotista y una nueva poesía de conciencia histórica que no solo retoma la historia y la realidad propias de Hispanoam

• O quilombo caracterizado como uma associa o guerreira

  2019-05-21

  

  O quilombo é caracterizado como uma associação guerreira aberta, sem distinção de linhagens e transcultural. A transculturalidade vem das contribuições de povos distintos, com destaque para os imbangala. No ritual de iniciação dos imbangala, SB 225002 circuncisão representava o rito de passagem que

• In addition we evaluated the left

  2019-05-21

  

  In addition, we evaluated the left atrium–left ventricle contraction sequence caused by the interatrial conduction delay. When we performed AV sequential pacing using the nominal AV delay setting, left atrial contractions were significantly delayed and were almost simultaneous with the left ventricu

• br Conflict of interest br Authors contributions br

  2019-05-21

  

  Conflict of interest Authors’ contributions Acknowledgements Introduction Aromatase-Inhibitors (AIs) are commonly used in the treatment of post-menopausal women with a history of hormone receptor-positive breast carcinoma, and have been shown to decrease bone mineral density (BMD) and in

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