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br Discussion Rarely a breast cancer patient has
2019-05-23
Discussion Rarely, a breast cancer patient has histologically proven breast cancer found outside the breast without a detectable primary breast tumor. Almost always the site of detected disease is an axillary lymph node. The incidence of axillary breast cancer with occult primary is relative low,
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Recently a reciprocal fusion between YPEL yippee
2019-05-23
Recently, a reciprocal fusion between YPEL5 (yippee-like 5) and PPP1CB (serine/threonine protein phosphatase-1 beta catalytic subunit) was described to be exclusively expressed in more than 90% of primary CLL samples [5] and not in control samples or samples from patients with other hematological m
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br Methods br Results br Discussion
2019-05-23
Methods Results Discussion One of the hallmarks of cancer is the ability of cancer strontium chloride to evade apoptosis. Inhibition of apoptosis not only enhances the survival of cancer cells but also facilitates their escape from chemotherapy [5]. Therefore, apoptosis regulatory mechanism
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br El a o pasado se
2019-05-23
El año pasado se presentó al público el libro de Pablo Monsanto (Jorge Ismael Soto) comandante de las Fuerzas Armadas Rebeldes y de la Unidad Revolucionaria Nacional Guatemalteca , titulado , el cual aporta información sobre varios pendientes sin resolver de la historia de la lucha revolucionaria
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Una participaci n de particular relevancia
2019-05-23
Una participación de particular relevancia fue la de Hugo Chávez en el Fsm 2006, pues su discurso puede considerarse una síntesis de la comprensión desde la política institucional latinoamericana de izquierdas sobre los movimientos sociales. En su discurso, Chávez convocó regadenoson la coordinación
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La fotograf a reforz el car
2019-05-23
La fotografía reforzó el carácter militarista del pgt-pc. El ajusticiamiento de Zepeda Martínez perdió su fuerza política al carecer de los mecanismos de propaganda que acompañan una acción de este tipo. Si bien los recursos gráficos explotados por el periodismo difundieron la muerte del cónsul, se
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br Since the publication of Stillbirths Series
2019-05-23
Since the publication of Stillbirths Series in 2011, attention to the more than 2·6 million stillbirths that occur every year has become more visible in global and national maternal and neonatal health strategies. However, we continue to neglect the millions of women who experience not only still
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Randomised controlled trials of educational
2019-05-22
Randomised controlled trials of educational interventions have also reported evidence to support the view that increased education is likely to be protective against infection. However, most education-focused trials are not designed to detect low-probability events such as HIV or to study the cumula
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In the APHRS survey most respondents answered
2019-05-22
In the APHRS survey, most respondents (86%) answered that OACs were discontinued before endoscopy or surgery. With novel OACs, physicians will be able to discontinue anticoagulant therapy before the surgical procedure without concern for thrombotic complications. The APHRS survey did not investigate
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Bafetinib Supplier br As the only methods available for dual
2019-05-22
As the only methods available for dual protection against pregnancy and sexually transmitted infections (STIs), male and female condoms have a vital role in sexual and reproductive health. Mags Beksinska and colleagues therefore are to be commended for their randomised crossover trial in this Bafe
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br Discussion ATRA and arsenic are both
2019-05-22
Discussion ATRA and arsenic are both known to induce differentiation syndrome but this case was notable for its severity. Previous studies of differentiation syndrome have demonstrated that APL mk-801 treated with ATRA secrete the chemokines CCL2 and IL-8, which in combination with chemokine pro
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br AML therapies with curative intent br
2019-05-22
AML therapies with curative intent Alternative treatment strategies Targeted therapies: the new kids on the block The recognition of specific mutations as genetic drivers or facilitators of AML has led to the development of new inhibitors and targeted treatment options. New promising drug c
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Interpretation The SMART course can give orthopaedic surgeon
2019-05-22
Interpretation The SMART course can give orthopaedic surgeons practising in LMICs the skills and knowledge to successfully perform flaps and reduce amputation. While this erk inhibitor course offers a collaborative, sustainable approach to reduce global surgery disparities in amputation, future inv
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Common and rare SCN A variants may contribute
2019-05-22
Common and rare SCN10A variants may contribute to AF susceptibility [59,60]. SCN10A mutations (R14L and R1268Q) cause a loss of function of Nav1.5 current, which is expected to reduce excitability and lead to the development of the arrhythmogenic substrate responsible for BrS and AF. A common varian
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It is noted that in this study BrS
2019-05-22
It is noted that in this study BrS patients had an abnormality of plasma K+ concentration which has been suggested to be a potential trigger of Brugada Syndrome episodes [11]. In the absence of renal dysfunction, the hyperkalemia may result from an abnormal phenotype in BrS characterized by mutation
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