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autophagy pathway br Materials and methods br Results br Dis
2018-11-14
Materials and methods Results Discussion Our study evaluated the significance of G protein-coupled signalling pathways on undifferentiated hESC maintenance under self-renewing conditions using a spectrum of pharmacological drugs and small autophagy pathway (the effects of which are summaris
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The role of NK cells in
2018-11-14
The role of NK EZ Cap Reagent GG (3\' OMe) in anti-tumour responses has been extensively studied, for various types of tumour, in animal models and humans (Vivier et al., 2012; Shafer et al., 2013; Velardi et al., 2012). Imai and colleagues reported that low peripheral NK cell cytotoxicity was assoc
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Kinase Inhibitor Library br Children who experience early li
2018-11-14
Children who experience early life seizures, prolonged febrile convulsions being the most common scenario, often have demonstrable problems with learning and memory later in life (). Although some of the children may go on to have epilepsy (recurrent unprovoked seizures) later in life, the problem
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HZ-1157 Supplier br HEV Mutations and Their Functional Role
2018-11-14
HEV Mutations and Their Functional Role RNA viruses exhibit high genetic variability by rapid evolution with estimated mutation rate ranging from 10 to 10 substitutions per nucleotide per strand copying (Sanjuan et al., 2010). The HEV mutation rates were estimated indirectly from clinical isolate
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br Declaration of Interests br Author
2018-11-14
Declaration of Interests Author Contributions Acknowledgments This work was supported by the EU FP7 project TBIcare (Project ref. 270259; to M.O., D.M., and O.T.), by the GE-NFL Head Health Challenge I Award (grant no. 7620 to M.O. and T.H.), by personal EVO funding (Finland) (to J.P.P and
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Although more GWAS on sepsis traits will
2018-11-14
Although more GWAS on sepsis traits will be accomplished in the coming years, it is worth noting that these studies allow analyzing a modest fraction of all existing variants in our genome. In , present their results from a study using a promising alternative taking advantage of high-throughput DNA
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Hypocretin producing neurons are localized in the hypothalam
2018-11-14
Hypocretin-producing neurons are localized in the hypothalamus (Hunt et al., 2015) and act via their two G-protein-coupled receptors, hypocretin receptor-1 and -2 (Hcrt-receptor-1 and Hcrt-receptor-2) (Sakurai et al., 1998). Hypocretin projections and Hcrt-receptors are found in many trospium chlori
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br Specifications table br Value of
2018-11-14
Specifications table Value of the data Experimental design, materials and methods HEK293 cell lines expressing either hAha1–Y223F–FLAG or Y223E–FLAG were grown in Dulbecco׳s modified Eagle׳s minimal essential medium (DMEM, Invitrogen) supplemented with 10% fetal bovine serum [1–4]. All cell
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Fig presents the EBSD micrographs obtained for the nanometri
2018-11-14
Fig. 3 presents the EBSD micrographs obtained for the nanometric powders. Analyzing these data revealed the lack of any preferential orientation. Relative densities were measured at 95.8% for the direct-SPS sample (a), and 93.9 for the CIP-SPS sample (b), with a relative density of the green sample
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br Experimental design materials and methods We selected the
2018-11-14
Experimental design, materials and methods We selected the four cultivars that are most widely farmed for food processing purposes. ‘Toyoshiro’ is the most popular cultivar and provides the highest yield for processing purposes in Japan [1]. ‘Kitahime’, ‘Snowden’ and ‘Poroshiri’ are predominantly
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br Conclusions br Acknowledgements This research
2018-11-14
Conclusions Acknowledgements This research was supported by Grant no. BMBF 01EV0711 (German Ministry of Education and Research) and by the IMAGEN Project (PL037286) of the European Commission\'s 6th Framework Program (LSHM-CT-2007-037286). We acknowledge support by the German Research Foundati
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br Study chasing versus inanimate motion br
2018-11-14
Study 1: chasing versus inanimate motion Study 2: chasing versus random General discussion Both studies postulate evidence of a strong positive amplitude for the chasing agent in the low occipital and post temporal areas 400ms post NHS-SS-Biotin onset. Given that prior research examining e
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At the neurophysiological level differences
2018-11-13
At the neurophysiological level, differences in visual input or visual drive may have lead to altered development of the social processing network (Eggebrecht et al., 2017). Facial expressions are processed in a specific network, including the posterior superior temporal sulcus, ventromedial prefron
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The first polysonogram in May demonstrated
2018-11-13
The first polysonogram, in May 2009, demonstrated increase in the percentage of slow waves, without other alterations. The electroencephalogram demonstrated diffuse slowing waves during crisis. The diagnosis was that of Kleine–Levin Syndrome and we initiated a reduction of venlafaxine to 37.5mg/day
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br Results and discussion The switching
2018-11-13
Results and discussion The switching acceleration for each of several switches is shown in Fig. 6 for the “cut and bend” design, and in Fig. 7 for the molded design. Each switch was left in the stressed stable state (shown in Figs. 3b and 5b) for a olopatadine hydrochloride of 2–3weeks, and each
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